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doi: 10.1016/j.chemosphere.2022.137433
EGCG was excreted through the bile and eliminated through the feces but not through the kidneys [43], possibly due to the hydrophobic gallated catechins bound to plasma protein that limited renal excretion as a result [44,45]
Notably, MAPKs can also influence cellular redox status: activated ERK enhances antioxidant gene expression, while JNK further exacerbates ROS production [39]

Pradefovir, though, was put on hold for further clinical testing after increased tumor incidence was observed in animal studies [55], but has recently moved forward with safety studies in healthy human subjects [56]

67 Latendresse JRI, Fisher JW
Rinse thoroughly and moisturize
