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The transporter returns to its initial structural conformation through a second ATP hydrolysis step, causing drug efflux (64, 65)

To match the systemic exposure of a 10mg subcutaneous dose, oral administration requires approximately 60100mg

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But milligrams describe the amount of active compound you want in your body

B ) Quantification of formate by NMR in the supernatants of mouse pancreatic cancer cell line, KPC-7 (CTL) or KPC-7 clones shown in extended data 3G, over-expressing ALDH1L2 (OE)