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Another possible explanation for this interaction may be increased distribution of valproate into erythrocytes

doi: 10.1016/j.cell.2017.04.001

Brain-derived neurotrophic factor reduces necrotic zone and supports neuronal survival after spinal cord hemisection in adult rats

Piglets suffering from intra-uterine growth restriction may exhibit irregular growth, characterised by normal growth of the brain and restricted growth of other organs such as the heart, and this is known as the brain-sparing effect (Reference Bauer, Walter and Brust4)

Whether pushed intentionally, or as an unintentional assumption, is unknown