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Concentrations were then corrected for these with the following formula: where [Mcorr] is the corrected concentration, [M] is the water-referenced metabolite concentration from the LCmodel output, fCSF is CSF fraction in the voxel, fGM is GM fraction in the voxel, and fWM is GM fraction in the voxel

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Essentially, the body ages and starts to put the sexual hormones and body parts on the back burner, but adding more DHEA can reduce this decline in sexual readiness