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This rapid clearance contributes to the favorable safety profile, as the compound itself does not accumulate in tissues
10.3390/molecules201219771 CrossRef Google Scholar View reference in article 119 ZhaoW.-Q.De FeliceF
What genetic factors predict who will experience GLP-1-related diarrhea
Notably, researchers observed that the rise in p21 levels, a marker of senescence, was independent of p53, indicating that, unlike many previous drugs, AKI603-induced senescence may operate independently of p53 activity [79]
McFarland et al
(4) This may lead to elevated levels of plasma growth hormone and insulin-like growth factor 1 (IGF-1)
