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In fact, GSNOR reacts with GSNO to generate oxidized glutathione disulfide (GSSG) and ammonia (NH3), thus reducing the concentration of S-nitroso alcohol

Codon-Improved Cre Recombinase (iCre), demonstrating to express at a higher level in mouse, was employed in most GemPharmatech Cre lines to allow high efficacy excision

10.1016/j.cbi.2016.01.020 Chem Biol Interact

Disruption of either system or of the NADPH-generating pathways they share
