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Description
Better for Severe Deficiencies: If someone has a significant B12 deficiency, oral supplements may not be enough to bring levels back up quickly

Similar to the effects of NNMT overexpression, hepatocytes treated with MNAM exhibited significant increases in glucose production and expression of Sirt1, G6pc, and Pck1

Vitamin B12 is a water-soluble vitamin essential for neurological function, DNA synthesis, and red blood cell formation

The NNMT enzyme it inhibits is constitutively expressed in adipose tissue and liver, meaning timing relative to meals is less critical than consistency
What are the benefits of B12 beyond energy

Funding and Disclosures: Westridge Foundation and the Canadian Institutes of Health and Research
