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While B complex vitamins are generally considered safe, high doses can cause side effects

Those taking certain medications - PPI medication, such as omeprazole, can reduce acid production in the stomach

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Research published in Science Translational Medicine (2015) demonstrated that elevated B12 levels can alter the gene expression patterns of these bacteria, specifically downregulating genes involved in B12 synthesis within the bacterial cells

Current safety data for 5-amino-1MQ appears favorable for short-term use (8-12 week cycles), with no significant toxicity observed in preclinical studies at therapeutic doses

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