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10.1016/j.intimp.2024.111791 32 ChenY.LiB.QuanJ.LiZ.LiY.TangY

N-acetylcysteine attenuates oxidative stress and liver pathology in rats with non-alcoholic steatohepatitis

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We hypothesized that the hepatic metabolome would be similarly characterized by increased alternative energy pathway utilization, altered redox balance and glutathione depletion, and reduced levels of ATP

The rectangular boxes and ovals contain the acronyms of the substrates and enzymes, respectively

This multi-core design maintained the viability of both probiotics (each core provided a protected micro-environment) and leveraged their synergistic interactions- the microcapsules exhibited enhanced acid resistance and in vivo efficacy, significantly reducing intestinal inflammation and improving metabolic markers in an animal model