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Increased as well as decreased activities of CAT from erythrocytes of SLE patients have been reported by various groups [46,48,49,57]

It is unknown, therefore, exactly how iron overload upsets neurotransmitter balance and causes anxiety and depressed symptoms (Uzungil et al., 2022

doi: 10.3389/fimmu.2024.1328858 Received 27 October 2023 Accepted 28 February 2024 Published 15 March 2024 Volume 15 - 2024 Edited by Motoko Koyama, Fred Hutchinson Cancer Center, United States Reviewed by Marie Bleakley, Fred Hutchinson Cancer Center, United States Daigo Hashimoto, Hokkaido University, Japan Updates Copyright 2024 Maurer and Antin

Relationship between physical activity and individual mental health after traumatic events: a systematic review

Another study provided similar results based on cuprizone model that the inactivation of astroglial NF-B dramatically prevented axonal loss through inhibiting proinflammatory cytokines and gliosis in GFAP-IB-dn mice (47)

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