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This is treated as an absolute contraindication across virtually every published research-community source

The guidelines here are a bit more flexible, but our professional recommendation is to stick with consistency

Medema, J

An immediate response to any symptoms is vital for the best outcomes

Increased Glutathione Biosynthesis by Nrf2 Activation in Astrocytes Prevents p75NTRDependent Motor Neuron Apoptosis. Journal of Neurochemistry 97: 687696

Kdm6a deficiency activates inflammatory pathways, promotes M2 macrophage polarization, and causes bladder cancer in cooperation with p53 dysfunction
