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doi: 10.1016/j.metabol.2010.07.023 [DOI] [PubMed] [Google Scholar] 27
Replication, rigor, and translation to longevity endpoints outside narrow cell assays are inconsistent in Western literature
[DOI] [Google Scholar] Yamabe S., Zeng G., Guan W., Sakaki S
doi:10.1016/j.mad.2005.05.002
By employing whole-genome haploid screening and CRISPR-Cas9 technology, two pivotal drivers of ferroptosis were identified: Acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3), both of which function as membrane remodeling enzymes [75,76,77]
