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(4) need of hemodialysis

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Certainly, there are people who have been identified with L-carnitine deficiency, often due to transporter issues (difficulty getting L-carnitine into cells, or absorbing it from the diet)

Moreover, given evidence that disruptions in fatty acid metabolism or -oxidation, such as increased serum acylcarnitines like palmitoyl-L-carnitine, affect mitochondrial dynamics and function [30, 31], we investigated whether palmitoyl-L-carnitine regulates mitochondrial fission or fusion

But is it really effective, or is it just another hyped-up product