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GPX4 knockdown keratinocytes appeared to have a decreased capacity for cell adhesion, along with accumulating lipid peroxides and enhanced levels of various pro-inflammatory elements, including COX-2, 4-HNE, and prostaglandins (Sengupta et al., 2013)

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HDAC6 and SIRT2 regulate the acetylation state and oncogenic activity of mutant KRAS

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