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In addition, genetic predisposition to ASIA has been reported, particularly among individuals carrying the HLA DRB1 haplotype (93)

found that the abnormal accumulation of double-stranded DNA in the cytoplasm may bind to the cytoplasmic DNA sensor (cGAS), thereby specifically triggering the STING-interferon (IFN) signaling pathway in microglia, promoting the expression and secretion of inflammatory cytokines

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48 Furthermore, TQ was the predominant bioactive compound extracted from Black cumin

[PubMed] [Google Scholar][140] Grisanti S, Biester S, Peters S, Tatar O, Ziemssen F, Bartz-Schmidt KU, Tuebingen Bevacizumab Study Group Intracameral bevacizumab for iris rubeosis