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These metabolites exhibit distinct pharmacological properties compared to parent THC, with 11-OH-THC reported to be more potent than THC, while THC-COOH is considered inactive but is often used as a plasma marker of cannabis consumption in drug tests [51,88]

doi: 10.3109/1061186X.2010.511225

Interactions of methylenedioxymethamphetamine with monoamine transmitter release mechanisms in rat brain slices

The concurrent inhibition of MEK (trametinib) and glutamine metabolism (V-9302) enhances antitumor efficacy by orchestrating the FOXO3a/FOXM1 axis and autophagy, leading to pyroptosis and cell cycle arrest (135)

Similarly, treatment of these cells with the Met-activating dimeric macrocycles aML5-PEG3, aMD4-PEG11 or aMD5-PEG11 restored cellular proliferation to a similar degree (Supplementary Fig

14 ChaoM
