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This review examines studies on iron metabolism, regulation via the hepcidin-ferroportin pathway, myocardial energy, oxidative stress, and clinical trials of iron supplementation or reduction in heart failure, chronic kidney disease, the elderly, women, and athletes

Combinatorial GeneGeneEnvironment CRISPR screen targeting human SLC25 transporter family enables the identification of SLC25A39 in mitochondrial glutathione import and its coordination with mitochondrial iron import in supporting OXPHOS.

notably, the loss of inner hair cell (IHC) synapses is considered a key underlying factor

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SSRIs, SNRIs: Heightened gastrointestinal bleeding risk

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