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doi: 10.3389/fendo.2013.00052 145 OsbornOOlefskyJM

In a systematic review and meta-analysis of four randomized controlled trials including over 3,700 subjects, combination therapy with an SGLT2 inhibitor and metformin beginning at diabetes diagnosis resulted in greater weight loss and reduction of HbA1C levels compared with either drug alone

Mild side effects may include nausea, upset stomach, headache, or restlessness

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5.1.8 Vitamins Studies indicate that vitamin D supplementation can lower LH levels in rat models of PCOS caused by EV, thus safeguarding ovarian tissue (78)

(NEPG), and Tokyo Chemical Industry Co., Ltd., now control the market in terms of market share