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Gliotoxin can target the 20S proteasome, which is responsible for the degradation of the IK-B protein that specifically binds to NF-B

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Budzianowska, A., Bana, K., Budzianowski, J., & Kikowska, M

The major members of the ROS family include free radicals like O 2 , OH and non-radicals like H 2 O 2 and 1 O 2