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Concurrent Targeting of Glutaminolysis and Metabotropic Glutamate Receptor 1 (GRM1) Reduces Glutamate Bioavailability in GRM1+ Melanoma

A meta-analysis of 15 randomized controlled trials showed modest BMI reduction with inositol supplementation, with the strongest evidence in PCOS populations where inositol improved insulin resistance and showed non-inferiority to metformin in 26 RCTs involving 1,691 patients

doi:10.1007/s12325-021-01789-5 Cai X, Liu M, Zhang B, Zhao SJ, Jiang SW

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