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FL: StatPearls
The best-understood epithelial sensors are enterochromaffin cells that primarily release serotonin (5-hydroxytryptamine, 5-HT) in response to mechanical or chemical stimuli

And, you know, 300s, 400s is a combination of environmental toxins and stress and modern day lifestyles or some of our hormone leading food system

[PubMed] [Google Scholar] Robert A

Of particular note is that enteric neurons make and release cytokines as well as classical neurotransmitters
