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Thromb Haemost 87:728734

Mild redness (less than 3 cm, fading within hours): Cold compress for 10 minutes No additional treatment needed Monitor for expansion Moderate redness (3 to 5 cm, lasting 1 to 3 days): Cold compress every 2 to 3 hours for first 24 hours Hydrocortisone 1% twice daily Ibuprofen 200 to 400mg if uncomfortable Significant redness (more than 5 cm, warm to touch, lasting more than 3 days): Cold compress protocol as above Hydrocortisone 1% twice daily Oral antihistamine daily Ibuprofen 400mg every 6 hours If not improving by day 5, contact healthcare provider Tracking the size of redness helps determine whether a reaction is improving or worsening

Its important to push yourself a bit, but not too much so that its not possible

Sterile technique for injections is essential to avoid infections

Much of the most cited evidence comes from wound healing contexts and cell culture studies rather than cosmetic outcomes measured in living skin over months

Another study was conducted in connection with this