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During these life stages, hyperinsulinemia is considered as part of the physiological responses against reduced insulin sensitivity elicited by growth hormones 85,86,87

The human relevance of such ALDOC changes was alternatively validated in an A-T cerebellar single-cell transcriptomic dataset 76 (Fig

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In the MBH and DVC, modules M4 and M14 respectively, expressed genes that are broadly impacting the neurons

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