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World J Gastroenterol, 2017

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However, its important to note that B12 shots are most beneficial for those who are truly deficient

For adults over 65, no dose adjustment is required, but careful monitoring for adverse effects is prudent as older adults often have multiple comorbidities and medications that increase complication risk

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Patients and healthcare professionals alike recognise that significant caloric restriction can lead to micronutrient deficiencies if dietary quality is not maintained