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It is likely that some steps of the biotransformation of arsenic that involve the formation of glutathione-bound species can occur also involving individual cysteine thiol groups or pairs of vicinal thiol groups in proteins, such as the catalytically essential thiol groups of enzymes and the regulatory elements of effector proteins that can be modulated by reversible glutathionylation (see further)

doi: 10.1016/j.cell.2015.08.030 2 ChoutkaJJansariVHornigMIwasakiA

Single cell analysis reveals multiple requirements for zinc in the mammalian cell cycle

Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction

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Pulmonary edema and pneumonia without hyaline membranes are other common findings, although 14% of patients do not have lung injuries, which may be attributed to atelectasis disguised as SARS [20,21]