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Using molecular docking, whole-cell and single-channel patch-clamp electrophysiology, and recordings in cultured hippocampal neurons, we show that EAR-20 enhances receptor function by increasing channel open probability and reducing desensitization, and can even activate NMDARs in the absence of exogenous glutamate and glycine, albeit to a lower extent

Dziaa na poziomie molekularnym i komrkowym, wspierajc dugowieczno komrek i tkanek, co czyni go obiecujcym rodkiem w terapii przeciwstarzeniowej i regeneracyjnej

, Almeida J

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In addition, curcumin positively regulates the differentiation and promotes the proliferation of osteoblasts, which play a crucial role in bone formation

Traumatic brain injury: mechanistic insight on pathophysiology and potential therapeutic targets