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Roche reported positive Phase II topline data showing that its once-weekly dual glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptor agonist CT-388 achieved substantial, sustained, and dose-dependent weight loss through 48 weeks

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There is no argument that the drugs are much more potent and faster acting than your bodies natural GLP-1 hormones

10, 2026 (GLOBE NEWSWIRE) -- Disclaimer: This article is for informational purposes only and does not constitute medical advice

The present study was designed to assess GLP-1-induced diuresis and natriuresis in rats with HF and its interactions with renal nerve activity

Combining lifestyle change, targeted metabolic support, and clinical guidance, it helps break the cardiometabolic cycle and build sustainable long-term health beyond short-term weight loss.