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GIP and GLP-1 dual agonists, such as Mounjaro, enable insulin secretion through activation of -cell GIP receptors and appear to greatly enhance the satiety and weight loss encountered with GLP-1R activation alone, aiding obesity [129,130]

Stress management influences digestive function through the gut-brain axis

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Gut microbes influence the availability and metabolism of neurotransmitter precursors, including tryptophan (a serotonin precursor) and tyrosine (a dopamine precursor), involved in mood regulation, cognition, and stress resilience

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