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Although epigenetic disorders can be transmitted via sperm [6,60,63], ROS may also affect the primary sperm DNA structure directly via the formation of DNA adducts such as 8-oxo deoxyguanosine: all of the nuclear bases may be affected by oxidation, but guanine is the most sensitive

Antioxidants donate an electron to free radical molecules, thereby neutralizing and stabilizing them

Further research is needed to fully understand the functional mechanism of NAC independent from GSH replenishment

[344] recently presented a very interesting study that not only summarized the latest findings on vitamin D in oxidative stress, but also showed the influence of short- and long-term vitamin D supplementations on the asthma symptoms in the serum, BALF, and lungs of OVA mice

The study of levels from redox-active elements in cerebrospinal fluid of amyotrophic lateral sclerosis patients carrying disease-related gene mutations shows potential copper dyshomeostasis