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Food and Drug Administration) (2020)

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Others reported increased p53 expression in malignant peripheral nerve sheath tumors compared with neurofibromas using a 30% cutoff

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The two major nutrient-sensing pathways that have been identified as key modulators of DR-induced longevity are LET-363/mTOR (mechanistic target of rapamycin) and IIS (insulin/insulin-like growth factor 1) signaling

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