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When levels drop, the symptoms can be subtle at first, then hard to ignore

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Each specimen was scored using a scale ranging from 03 (0: none, 1: mild, 2: moderate, and 3: severe) for each criterion and a final histology score was determined [55]

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10.1186/s13229-015-0062-8 207 MinshewN

Efficacy and safety of Mirikizumab in a randomized Phase 2 study of patients with ulcerative colitis