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Specifically, AST suppresses the expression of lncITPF by inhibiting the phosphorylation and nuclear translocation of Smad3, thereby reducing the expression of its target gene ITGBL1

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doi: 10.1016/j.envexpbot.2017.06.008 [DOI] [Google Scholar] Wei C., Jiao Q., Agathokleous E., Liu H., Li G., Zhang J., et al

Our secondary outcome was to evaluate the tolerability of oral glutathione in children with ASD

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It was shown that the toxicity of OTA could be decreased by maintaining glutathione production with N -acetyl cysteine (NAC), which decreased reactive oxygen species (ROS) and 8-oxoguanine formation