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Central cyanosis may be due to the following causes: Central nervous system (impairing normal ventilation): [5] Respiratory system: [1] [5] Cardiovascular system: [1] [5] Hemoglobinopathies: [5] Methemoglobinemia [a] Sulfhemoglobinemia [b] Polycythemia Congenital cyanosis (HbM Boston) arises from a mutation in the -codon which results in a change of primary sequence, H Y

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