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molecular size is also important

Poon, W., Kingston, B

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Human colon cancer HCT116 cells that were incubated with mG/AIDA-BL21 bacteria were sensitive to a glucuronide prodrug (p-hydroxy aniline mustard -D-glucuronide, HAMG) with an half maximal inhibitory concentration (IC 50 ) value of 226.5345.4 M, similar to the IC 50 value of the active drug (p-hydroxy aniline mustard, pHAM

High concentrations of actives like Vitamin C, niacinamide, or AHAs can cause irritation, inflammation, and paradoxically worsen pigmentation especially in deeper skin tones

Notably, vitamin B6-conjugated compounds are internalized through putative VTC-dependent pathways in cancer cells that exhibit increased dependency on vitamin B6