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The main source of hydrogen peroxide is formed by SOD-catalyzed superoxide radical dismutation reaction, but it also can be formed by two-electron reduction of oxygen in the reactions catalyzed by oxidases such as xanthine oxidase, glucose oxidase, and others

Audet et al., 2012) and will not be discussed further here, a large body of evidence suggests that different agonists exhibit bias for G protein interaction versus phosphorylation by different kinases and endocytosis as discussed below