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These finding suggested that melatonin can be effectively use as nephroprotective adjunct to ameliorate the oxidative stress, inflammatory process and renal metabolic impairments in ifosfamide nephrotoxicity

cancer cells compete for methionine through SLC43A2, which impairs STAT5 expression in T cells, affecting histone methylation and their function

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PMID: 5 BozhedomovVALipatovaNARokhlikovIMAlexeevRAUshakovaIVSukhikhGT

CSCs are tumorigenic (tumor-forming), perhaps in contrast to other non-tumorigenic cancer cells