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CYP3A4 and CYP3A5: the crucial roles in clinical drug metabolism and the significant implications of genetic polymorphisms

GPCRs are brought into an active conformational state by interacting with exogenous or endogenous agonists, which then affect the intracellular binding of G-proteins or arrestin proteins

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Oxidative stress-mediated lead toxicity is known to cause perturbations in brain function

Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination

Milbrandt, J