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Conflicts of Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: the figures in the review except Figure 1 and Figure 2 were drawn by Figdraw

Upon injection of the high number of cells, control mice develop local and distant tumours by about 3-4 weeks

Uneven Drug Distribution Injections may not diffuse uniformly, leading to inhibition in certain muscle bundles, whereas unaffected bundles may compensate by increasing stimulus signals

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Lasers Med Sci 18:128133 Juarranz A, Jan P, Sanz-Rodrguez F, Cuevas J, Gonzlez S (2008) Photodynamic therapy of cancer