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179 Interestingly, ROCK inhibitor was also shown to inhibit lipopolysaccharide (LPS)-induced MLC phosphorylation and occludin downregulation

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Clarke JR, Lyra E, Silva NM, Figueiredo CP, Frozza RL, Ledo JH, Beckman D, Katashima CK, Razolli D, Carvalho BM, Frazo R, Silveira MA, Ribeiro FC, Bomfim TR, Neves FS, Klein WL, Medeiros R, LaFerla FM, Carvalheira JB, Saad MJ, Munoz DP, Velloso LA, Ferreira ST, De Felice FG (2015) Alzheimer-associated A oligomers impact the central nervous system to induce peripheral metabolic deregulation