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The trade-off is a higher incidence of gastrointestinal side effects

While these pharmacological agents provide rapid symptom relief, they are associated with notable side effects such as mucosal thinning, skin atrophy, dependency, and gastrointestinal discomfort when used long-term

In: Genetic disorders in glutathione and sulfur amino-acid metabolism

Understanding Melanin Production and UV Damage UV radiation triggers a cascade of cellular responses, increasing melanin synthesis as a protective mechanism

I., Ituarte, P

Additionally, ROS can oxidize amino acids leading to DNA strand breakage and DNA protein crosslinking resulting in mutations