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Functional diversity to the individual methylation sites is provided by the fact that lysine can be mono-, di- or trimethylated
In principal cells derived from rodent hippocampus, an acute elevation in O-GlcNAcylation was observed to attenuate GABAergic currents and reduce synaptic spikes through synaptic depression and reduced intrinsic excitability [70]
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Therefore, these mass analyzers are now rarely used in LCMS systems
[DOI] [PubMed] [Google Scholar] 51.Stupnisek M, Kokot A, Drmic D, Hrelec Patrlj M, Zenko Sever A, Kolenc D, Radic B, Suran J, Bojic D, Vcev A, et al
Hall et al., 2016)
