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To explore whether targeted intervention of Chac2 in neutrophils could alleviate the inflammatory comorbidity of periodontitis, we constructed AAV9 viruses targeting neutrophils to specifically knock down Chac2 (AAV-shCHAC2) and a control virus with no payload (AAV-NC), and administered them via intraosseous injection into a mouse model with periodontitis and diabetes comorbidity

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Generation by hydrogenation of DHCMT of 4-chloromethyltestosterone failed due to a concomitant loss of chlorine

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If a lumbar puncture is performed: Consider obtaining an autoimmune encephalitis panel and oligoclonal bands