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References Noctor, G., Cohen, M., Trmulot, L., et al

Supporting Phase II Detoxification often involves nutritional strategies, as many of the enzymes and conjugating agents require specific vitamins, minerals, and amino acids

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E N D Presentation Transcript Phase-II Drug Metabolism Reactions which conjugate the drug or its phase-I metabolite with a hydrophilic, endogenous species (conjugation reactions)

On the functional level, CNS inflammation has been associated with cytokine-mediated sickness behavior (Dantzer, 2009), excitotoxicity (Dong et al., 2009) and dysfunctional connectivity within the brain (notably due to synaptic loss and demyelination) (Rao et al., 2012) that leads to CNS dysfunction affecting sleep, circadian rhythm, emotional processing, cognition, learning and memory, pain, and autonomous regulation

This may be a sign of a minor allergic reaction, but its important to monitor the symptoms
