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Zhang, H., Go, Y.-M
Braha, B., Simm, C., Clemens, S

In their meta-analysis, Kosmas et al

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[It] also aids in DNA synthesis and is involved in the metabolism of carbohydrates, fats, and proteins." Because it's so important, those with this type of vitamin deficiency, which is diagnosed via a blood test, are usually recommended to take either supplements or get regular B12 shots