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Phase I clinical trials revealed that EZN-2698 is a potential agent in patients with advanced renal cell carcinoma (RCC)
55,56 A great deal of evidence shows that DNA damage caused by ionizing radiation or intrinsic ROS can be repaired by base excision

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CNS Neurol Disord Drug Targets 17:689695 Kielian T, Barry B, Hickey WF (2001) CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses

These metal-binding cysteine-rich proteins are responsible for maintaining zinc-related cell homeostasis and act as potent electrophilic scavengers and cytoprotective agents

Increased levels of AZIN1 mRNA editing has been shown to occur in certain types of cancer
