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Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity
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Class III, which includes the NAD+-dependent sirtuins (SIRTs)

It may also be linked to other benefits and could aid in the treatment of conditions such as depression and nonalcoholic fatty liver disease (NAFLD)

The strongest evidence supports its role in skin repair and wound healing
Cannistraci, A