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Expression of AFP, HNF4A, SOX9 and GATA4 is relatively similar in both GF-HLCs and SM-HLCs (Figure 2D)

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Although the exact mechanism for this weight-reducing effect is unknown, the proposed mechanism includes alterated perception of taste due to carbonic anhydrase activity and modulation of dopamine and serotonin levels in the brain [241, 244, 245].Empatic has shown promising results in phase 2 clinical trials [241] (Table 2 )

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They work best when layered into a foundation of factors that contribute to optimal body composition: Adding regular physical activity, combined with peptides, can enhance overall health and body composition

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ER has less of a role in the classical estrogen target tissues and has been found to be more dominant in the brain, cardiovascular system and the colon [87, 88]

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Biological passport evolution The Athlete Biological Passport tracks biomarkers over time rather than testing for specific substances

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