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Recent Developments/ Strategic Initiatives 8.5.4

These results are based on 22 comparisons for HHF and 18 comparisons for the renal outcome

November 2023 : Eli Lilly received US FDA approval for ZEPBOUND, an obesity treatment that activates GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) hormone receptors

The combined effect is greater than either lever alone, which is why 15 mg of tirzepatide produces weight loss that 2.4 mg of semaglutide cannot match

Cone said the idea these drugs could influence the brains reward pathways isnt a stretch we need to eat to survive, so we evolved to derive pleasure from the experience as an incentive

Genetic Predispositions and Individual Variability in IBD Populations Genetic factors influencing GLP-1 receptor expression and intestinal inflammation overlap significantly