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Unraveling these interactions is not only crucial for understanding pharmacological mechanisms but also for unlocking the untapped potential of natural products in various applications
To view a copy of this licence, visit About this article Cite this article Kuntic, I., Kuntic, M., Oelze, M
E.KarolyH
10.1056/NEJM198103053041004 107
The accumulation of intracellular ROS caused by low levels of tert-butyl hydroperoxide can induce the activation of p53 and lead to cell death, which can be specifically inhibited by the ferroptosis inhibitor Fer-1 but cannot be inhibited by other kinds of cell death pathway inhibitors, indicating that the form of death is ferroptosis
