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1,2,18 Table 3 lists the relative sensitivities and specificities of various laboratory tests

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To validate the pathogenicity of GPX4 variants, we will analyze patient-derived fibroblasts for hallmarks of oxidative stress and ferroptosis

Limitations of traditional mechanistic frameworks Traditional models of CVD-cognitive impairment comorbidity primarily focus on vascular-mediated processes, including cerebral hypoperfusion, where arterial stenosis or HF-induced reduction in blood flow impairs the delivery of oxygen and nutrients to neurons

Medication BPC 157 (10 g/kg, 10 ng/kg) was applied either intraperitoneally once time daily (first application immediately after surgery, last at 24 hours before sacrifice) or per-orally in drinking water (0.16 g/ml/12 ml/day till the sacrifice) while controls simultaneously received an equivolume of saline (5 ml/kg) intraperitoneally or drinking water only (12 ml/day)